UBC13 Antibodies

Antibodies that detect UBC13 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Immunoprecipitation. These antibodies target UBC13 in Human, Mouse, Rat and Non-human primate samples. Our UBC13 polyclonal,... Antibodies that detect UBC13 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Immunoprecipitation. These antibodies target UBC13 in Human, Mouse, Rat and Non-human primate samples. Our UBC13 polyclonal, recombinant monoclonal and monoclonal... Antibodies that detect UBC13 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Immunoprecipitation. These antibodies target UBC13 in Human, Mouse, Rat and Non-human primate samples. Our UBC13 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Knockdown, Relative expression and Cell treatment to confirm specificity to UBC13. Find the UBC13 antibody that fits your needs. Choose from 1 of 16 UBC13 antibodies, which have been validated in experiments with 58 publications and 67 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA,... Antibodies that detect UBC13 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Immunoprecipitation. These antibodies target UBC13 in Human, Mouse, Rat and Non-human primate samples. Our UBC13 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Knockdown, Relative expression and Cell treatment to confirm specificity to UBC13. Find the UBC13 antibody that fits your needs. Choose from 1 of 16 UBC13 antibodies, which have been validated in experiments with 58 publications and 67 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Acts together with the E3 ligases, HLTF and SHPRH, in the 'Lys-63'-linked poly-ubiquitination of PCNA upon genotoxic stress, which is required for DNA repair. Appears to act together with E3 ligase RNF5 in the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD. Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes. Together with RNF135 and UB2V1, catalyzes the viral RNA-dependent 'Lys-63'-linked polyubiquitination of RIG-I/DDX58 to activate the downstream signaling pathway that leads to interferon beta production. UBE2V1-UBE2N together with TRAF3IP2 E3 ubiquitin ligase mediate 'Lys-63'-linked polyubiquitination of TRAF6, a component of IL17A-mediated signaling pathway. (Uniprot)

同义词

1500026J17Rik; AL022654; BB101821; bendless protein; bendless-like ubiquitin conjugating enzyme; bendless-like ubiquitin-conjugating enzyme; Blu; E2 ubiquitin-conjugating enzyme N; epididymis secretory protein Li 71; HEL-S-71; MGC131857; MGC8489; UBC13; UbcH13; UbcH-ben; UBCHBEN; UBC13; UBE2N; Ubiquitin carrier protein N; ubiquitin conjugating enzyme E2 N; ubiquitin conjugating enzyme E2N; ubiquitin-conjugating enzyme E2 N; ubiquitin-conjugating enzyme E2N; ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13); ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast); ubiquitin-protein ligase N; yeast UBC13 homolog

UBC13 Antibodies

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