Antibodies that detect ULK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target ULK1 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our ULK1 polyclonal,...Antibodies that detect ULK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target ULK1 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our ULK1 polyclonal, recombinant monoclonal and monoclonal...Antibodies that detect ULK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target ULK1 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our ULK1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Sheep and Mouse. These antibodies have been verified by Cell treatment to confirm specificity to ULK1. Find the ULK1 antibody that fits your needs. Choose from 1 of 47 ULK1 antibodies, which have been validated in experiments with 70 publications and 110 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications....
Antibodies that detect ULK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target ULK1 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our ULK1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Sheep and Mouse. These antibodies have been verified by Cell treatment to confirm specificity to ULK1. Find the ULK1 antibody that fits your needs. Choose from 1 of 47 ULK1 antibodies, which have been validated in experiments with 70 publications and 110 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
ULK1 is a serine/threonine protein kinase that plays critical role during initial stages of autophagy which is a vital response to nutrient starvation. The conserved C-terminal domain (CTD) of ULK1 controls the regulatory function and localization of the protein. Knockdown of ULK1 inhibits the autophagic response as well as inhibiting rapamycin-induced autophagy consistent with a role downstream of mTOR. ULK1 forms a complex with FIP200 and ATG13 and this complex is essential for starvation-induced autophagy. Both FIP200 and ATG13 are critical for correct localization of ULK1 to the pre-autophagosome and stability of ULK1 protein. ULK1 is phosphorylated by the mTOR pathway in a nutrient starvation-regulated manner.
同义词
APG1; ATG 1; ATG1; ATG1 autophagy related 1 homolog; ATG1A; AU041434; Autophagy-related protein 1 homolog; C. elegans; EC:2.7.11.1; FLJ38455; hATG1; KIAA0722; mKIAA0722; Serine/threonine-protein kinase ULK1; serine/threonine-protein kinase Unc51.1; ULK 1; Ulk1; UNC 51; UNC51; unc-51 like autophagy activating kinase 1; unc-51 like kinase 1; Unc51.1; unc-51-like kinase 1
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