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Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.
DKFZp686H12131; lew; MRXSYP; SPAX1; SYB1; Syb-1; synaptobrevin 1; synaptobrevin-1; vamp; Vamp1; VAMP-1; vesicle associated membrane protein 1; vesicle-associated membrane protein 1; vesicle-associated membrane protein 1 (synaptobrevin 1)
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