Antibodies that detect VDR can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and ELISA. These antibodies target VDR in Human, Mouse, Rat, Chicken and Amphibian samples. Our VDR polyclonal, recombinant...Antibodies that detect VDR can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and ELISA. These antibodies target VDR in Human, Mouse, Rat, Chicken and Amphibian samples. Our VDR polyclonal, recombinant monoclonal and monoclonal antibodies...Antibodies that detect VDR can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and ELISA. These antibodies target VDR in Human, Mouse, Rat, Chicken and Amphibian samples. Our VDR polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse, Rat and Goat. These antibodies have been verified by Knockdown and Cell treatment to confirm specificity to VDR. Find the VDR antibody that fits your needs. Choose from 1 of 24 VDR antibodies, which have been validated in experiments with 168 publications and 97 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other...
Antibodies that detect VDR can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and ELISA. These antibodies target VDR in Human, Mouse, Rat, Chicken and Amphibian samples. Our VDR polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse, Rat and Goat. These antibodies have been verified by Knockdown and Cell treatment to confirm specificity to VDR. Find the VDR antibody that fits your needs. Choose from 1 of 24 VDR antibodies, which have been validated in experiments with 168 publications and 97 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. The 1,25-dihydroxy-vitamin D3 receptor (VDR) belongs to the superfamily of steroid hormone receptors which includes estrogen, progesterone, glucocorticoid, androgen, and thyroid hormone receptors. Vitamin D modulates calcium and phosphorus homeostasis, bone remodeling, cell growth regulation, and differentiation. Studies have found VDR in the intestine, bone, kidney, epidermis, and cells of the endocrine immune system. Repression of T-cell proliferation and interleukin-2 (IL-2) gene expression, for example, occurs when VDR binds within the IL-2 enhancer. Formation of VDR/retinoic X receptor (RXR) heterodimers in the presence of intracellular 1,25(OH)2D3 has been shown to interfere with assembly of nuclear factor of activated T-cells (NFATp)/Fos/Jun/DNA complex and subsequent IL-2 gene transcription. The corresponding gene for the vitamin D receptor is NR1I1.
同义词
1,25-dihydroxyvitamin D3 receptor; HGNC:12679; I79_025795; Nr1i1; Nuclear receptor subfamily 1 group I member 1; PPP1R163; protein phosphatase 1, regulatory subunit 163; vdr; vdr.S; vdr-A; vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D (1,25- dihydroxyvitamin D3) receptor S homeolog; vitamin D (1,25-dihydroxyvitamin D3) receptor; vitamin D nuclear receptor variant 1; vitamin D receptor; vitamin D receptor protein; vitamin D receptor S homeolog; Vitamin D3 receptor; XELAEV_18015993mg; xVDR
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