Antibodies that detect WTAP can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target WTAP in Human, Mouse, Rat and Non-human primate samples. Our WTAP monoclonal,...Antibodies that detect WTAP can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target WTAP in Human, Mouse, Rat and Non-human primate samples. Our WTAP monoclonal, polyclonal and recombinant...Antibodies that detect WTAP can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target WTAP in Human, Mouse, Rat and Non-human primate samples. Our WTAP monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the WTAP antibody that fits your needs. Choose from 1 of 36 WTAP antibodies, which have been validated in experiments with 95 publications and 216 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the...
Antibodies that detect WTAP can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target WTAP in Human, Mouse, Rat and Non-human primate samples. Our WTAP monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the WTAP antibody that fits your needs. Choose from 1 of 36 WTAP antibodies, which have been validated in experiments with 95 publications and 216 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Wilms' tumor (WT) is an embryonal malignancy of the kidney that affects 1 in 10,000 infants and is observed in both sporadic and inherited forms. The Wilms' tumor protein (WT1) binds the DNA sequence GCGGGGGCG, a recognition element common to the early growth response (Egr) family of Zn2+ finger transcriptional activators, and functions as a transcriptional repressor. WTAP (Wilms tumor 1-associating protein) is a ubiquitously expressed nuclear protein that interacts with WT1 and may be involved in regulating mRNA splicing. WTAP is found in nuclear speckles, where it regulates the G2/M cell cycle transition by binding to the 3' UTR of cyclin A2, thus enhancing its stability. Additionally, WTAP inhibits expression of WT1 target genes and is able to impair the ability of WT1 to bind DNA. Two isoforms of WTAP exist due to alternative splicing events.
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