Product References
Selective vulnerability of human-induced pluripotent stem cells to dihydroorotate dehydrogenase inhibition during mesenchymal stem/stromal cell purification.
Frontiers in cell and developmental biology
Al-Akashi Z,Zujur D,Kamiya D,Kato T,Kondo T,Ikeya M
12-8863-82 was used in Flow cytometry/Cell sorting to demonstrates the Brequinar (BRQ)-induced inhibition of dihydroorotate dehydrogenase (DHODH), a key enzyme in de novo pyrimidine biosynthesis, selectively induces apoptosis, cell cycle arrest, and differentiation; furthermore, it promotes transcriptional changes and prevents the growth of 3-dimensional hiPSC aggregates.
Fri Feb 24 00:00:00 EST 2023
Characterization of intracellular buffering power in human induced pluripotent stem cells and the loss of pluripotency is delayed by acidic stimulation and increase of NHE1 activity.
Journal of cellular physiology
Lee SP,Chao SC,Chou MF,Huang SF,Dai NT,Wu GJ,Tsai CS,Loh SH,Tsai YT
12-8863-82 was used in Flow cytometry/Cell sorting to establish a quantitative model of passive β during differentiation and demonstrate that maintenance of NHE1 at a higher level is of critical importance for pluripotency retention in hiPSCs.
Mon Feb 01 00:00:00 EST 2021
Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells.
Cell reports
Wang K,Guzman AK,Yan Z,Zhang S,Hu MY,Hamaneh MB,Yu YK,Tolu S,Zhang J,Kanavy HE,Ye K,Bartholdy B,Bouhassira EE
12-8863-82 was used in Flow Cytometry to suggest LT-HSCs may become the preferred cell source for the production of clinical-grade iPSCs.
Tue Mar 05 00:00:00 EST 2019
Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity.
Cell stem cell
Carcamo-Orive I,Hoffman GE,Cundiff P,Beckmann ND,D'Souza SL,Knowles JW,Patel A,Papatsenko D,Abbasi F,Reaven GM,Whalen S,Lee P,Shahbazi M,Henrion MYR,Zhu K,Wang S,Roussos P,Schadt EE,Pandey G,Chang R,Quertermous T,Lemischka I
12-8863 was used in Immunocytochemistry to examine the sources of gene expression variability in 317 human induced pluripotent stem cell lines from 101 individuals.
Thu Apr 06 00:00:00 EDT 2017
Comparison of Four Protocols to Generate Chondrocyte-Like Cells from Human Induced Pluripotent Stem Cells (hiPSCs).
Stem cell reviews and reports
Suchorska WM,Augustyniak E,Richter M,Trzeciak T
Published figure using TRA-1-60 (Podocalyxin) monoclonal antibody (Product # 12-8863-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes.
Stem cell reports
Oleksiewicz U,Gładych M,Raman AT,Heyn H,Mereu E,Chlebanowska P,Andrzejewska A,Sozańska B,Samant N,Fąk K,Auguścik P,Kosiński M,Wróblewska JP,Tomczak K,Kulcenty K,Płoski R,Biecek P,Esteller M,Shah PK,Rai K,Wiznerowicz M
Published figure using TRA-1-60 (Podocalyxin) monoclonal antibody (Product # 12-8863-82) in Flow Cytometry
Tue Dec 12 00:00:00 EST 2017
A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening.
Genome research
Diao Y,Li B,Meng Z,Jung I,Lee AY,Dixon J,Maliskova L,Guan KL,Shen Y,Ren B
12-8863 was used in Flow cytometry/Cell sorting to demonstrate the utility of high-throughput screening for noncoding DNA functional characterisation and reveal a novel layer of gene regulation in humans.
Tue Mar 01 00:00:00 EST 2016
Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome.
Journal of the American Heart Association
Jouni M,Si-Tayeb K,Es-Salah-Lamoureux Z,Latypova X,Champon B,Caillaud A,Rungoat A,Charpentier F,Loussouarn G,Baró I,Zibara K,Lemarchand P,Gaborit N
12-8863 was used in Flow cytometry/Cell sorting to evaluate the use of cardiomyocytes differentiated from urine-derived stem cells as a new cellular model for studying patients' specific arrhythmia mechanisms.
Tue Sep 01 00:00:00 EDT 2015
Autophagy regulates homeostasis of pluripotency-associated proteins in hESCs.
Stem cells (Dayton, Ohio)
Cho YH,Han KM,Kim D,Lee J,Lee SH,Choi KW,Kim J,Han YM
12-8863 was used in Flow cytometry/Cell sorting to demonstrate that autophagy acts together with the ubiquitin-proteasome system to modulate the levels of pluripotency-associated proteins in human embryonic stem cells.
Sat Feb 01 00:00:00 EST 2014
PRMT5 is required for human embryonic stem cell proliferation but not pluripotency.
Stem cell reviews and reports
Gkountela S,Li Z,Chin CJ,Lee SA,Clark AT
Published figure using TRA-1-60 (Podocalyxin) monoclonal antibody (Product # 12-8863-82) in Flow Cytometry
Tue Apr 01 00:00:00 EDT 2014
Few single nucleotide variations in exomes of human cord blood induced pluripotent stem cells.
PloS one
Su RJ,Yang Y,Neises A,Payne KJ,Wang J,Viswanathan K,Wakeland EK,Fang X,Zhang XB
12-8863 was used in Flow cytometry/Cell sorting to study the effect of the cellular reprogramming process on mutation load in induced pluripotent stem cells.
Tue Oct 22 00:00:00 EDT 2013
Procedures for derivation and characterisation of human embryonic stem cells from Odense, Denmark.
Methods in molecular biology (Clifton, N.J.)
Harkness L,Kassem M
12-8863-82 was used in flow cytometry to describe the derivation methods used by our laboratory for isolation of the ICM by immunosurgery and outgrowth of the whole blastocyst.
Fri Aug 10 00:00:00 EDT 2012