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Invitrogen
Complex III Monoclonal Antibody (11A51H12), Agarose
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FIGURE: 1 / 1
Complex III Antibody (45-7125) in IP
Immunoprecipitation analysis of UQCRC1 using a UQCRC1 Monoclonal antibody (Product # 45-7125). Each lane was immunoprecipitated using the UQCRC1 Monoclonal antibody (Product # 45-7125) at a concentration of 10 µg/mg of lysate. Lane 1: 0.1mg of Bovine mitochondria, Lane 2: 0.05mg Bovine mitochondria, Lane 3: 0.05mg Human mitochondria.
Product Details
45-7125
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
11A51H12
Immunogen
Bovine Heart Complex III
Conjugate
Form
Liquid
Purification
Ammonium sulfate precipitation
Storage buffer
HEPES buffered saline
Contains
0.02% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Complex III, or ubiquinol cytochrome c oxidoreductase, is a complex of 11 subunits and catalyses electron transfer from reduced ubiquinone or coenzyme Q 10 to cytochrome c. The complex contains 11 different subunits, one of which, cytochrome b, is encoded on mitochondrial DNA, while the remainder subunits are nuclear-encoded. Genetic complex III deficiencies occur but are rare.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Complex III subunit 1; Complex III subunit 10; Complex III subunit 2; Complex III subunit 3; Complex III subunit 4; Complex III subunit 5; Complex III subunit 6; Complex III subunit 7; Complex III subunit 8; Complex III subunit 9; Complex III subunit III; Complex III subunit IV; Complex III subunit VII; Complex III subunit VIII; Complex III subunit X; Complex III subunit XI; Core protein I; Core protein II; Cytochrome b; Cytochrome b-c1 complex subunit 1, mitochondrial; Cytochrome b-c1 complex subunit 10; Cytochrome b-c1 complex subunit 2, mitochondrial; Cytochrome b-c1 complex subunit 3; Cytochrome b-c1 complex subunit 4; Cytochrome b-c1 complex subunit 5; Cytochrome b-c1 complex subunit 6, mitochondrial; Cytochrome b-c1 complex subunit 7; Cytochrome b-c1 complex subunit 8; Cytochrome b-c1 complex subunit 9; Cytochrome b-c1 complex subunit Rieske, mitochondrial; cytochrome bc-1 complex core protein II; Cytochrome c-1; Cytochrome c1 non-heme 11 kDa protein; Cytochrome c1 non-heme 7 kDa protein; Cytochrome c1, heme protein, mitochondrial; cytochrome C1, nonheme 11 kDa protein; cytochrome C1, nonheme 7kDa protein; Liver regeneration-related protein LRRGT00195; Low molecular mass ubiquinone-binding protein; low molecular mass ubiquinone-binding protein (9.5kD); low molecular mass ubiquinone-binding protein (Qpc-pending); Mitochondrial hinge protein; mitochondrial ubiquinone-binding protein; QP-C; Rieske iron-sulfur protein; Rieske iron-sulfur protein precursor; Rieske protein UQCRFS1; RISP; ubiquinol cytochrome c reductase hinge protein; ubiquinol cytochrome c reductase, 6.4kDa subunit; ubiquinol-cytochrome c reductase (6.4kD) subunit; ubiquinol-cytochrome c reductase binding protein; ubiquinol-cytochrome c reductase binding protein-like; ubiquinol-cytochrome c reductase complex (7.2 kD); Ubiquinol-cytochrome c reductase complex 11 kDa protein; Ubiquinol-cytochrome c reductase complex 14 kDa protein; Ubiquinol-cytochrome c reductase complex 6.4 kDa protein; Ubiquinol-cytochrome c reductase complex 7.2 kDa protein; ubiquinol-cytochrome c reductase complex 7.2kDa protein; Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; ubiquinol-cytochrome C reductase complex core protein 2, mitochondrial precursor (Complex III subunit II); ubiquinol-cytochrome c reductase complex protein; Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C; ubiquinol-cytochrome c reductase core protein 1; ubiquinol-cytochrome c reductase core protein I; ubiquinol-cytochrome c reductase core protein II; Ubiquinol-cytochrome c reductase iron-sulfur subunit; ubiquinol-cytochrome c reductase subunit; ubiquinol-cytochrome c reductase, 6.4kDa subunit; ubiquinol-cytochrome c reductase, complex III subunit VI; ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa; ubiquinol-cytochrome c reductase, complex III subunit VIII; ubiquinol-cytochrome c reductase, complex III subunit X, 7.2kDa; ubiquinol-cytochrome c reductase, complex III subunit XI; Ubiquinol-cytochrome-c reductase complex core protein 1; Ubiquinol-cytochrome-c reductase complex core protein 2; Ubiquinol-cytochrome-c reductase complex cytochrome b subunit; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit
Gene Aliases: 0710008D09Rik; 1100001F06Rik; 1110020P15Rik; 1110032G10Rik; 1500004O06Rik; 1500040F11Rik; 2210415M14Rik; 2210416J04Rik; 2310021J10Rik; 2610002H19Rik; 2610041P16Rik; 4430402G14Rik; 5830407L17Rik; 9.5kDa; AA408921; AA959903; AA960494; AI875505; AL022707; c1502; COB; CYC1; CYTB; D3S3191; HSPC051; HSPC119; HSPC151; LRRGT00195; MC3DN3; MC3DN4; MC3DN5; MC3DN6; MT-CYB; MTCYB; QCR1; QCR10; QCR2; QCR6; QCR7; QCR8; QCR9; QP-C; QPC; RIP1; RIS1; RISP; UCCR7.2; UCRC; UQBC; UQBP; UQCR; UQCR1; UQCR10; UQCR11; UQCR2; UQCR4; UQCR5; UQCR6; UQCR7; UQCR8; UQCRB; Uqcrbl; UQCRC1; UQCRC2; UQCRFS1; UQCRH; UQCRQ; UQPC
UniProt ID: (Human) P08574, (Bovine) P00125, (Mouse) Q9D0M3, (Bovine) P00130, (Human) Q9UDW1, (Human) O14957, (Bovine) P07552, (Bovine) P00129, (Human) P14927, (Bovine) P31800, (Human) P31930, (Human) P22695, (Bovine) P13272, (Human) P47985, (Bovine) P00126, (Human) P07919, (Bovine) P13271, (Human) O14949, (Mouse) Q8R1I1, (Mouse) Q9CPX8, (Rat) Q68FY0, (Mouse) Q9CZ13, (Mouse) Q9DB77, (Rat) P32551, (Mouse) Q9CR68, (Rat) P20788, (Rat) Q5M9I5, (Mouse) P99028, (Mouse) Q9CQ69, (Rat) Q7TQ16
Entrez Gene ID: (Human) 1537, (Bovine) 512500, (Rat) 300047, (Mouse) 66445, (Bovine) 616109, (Human) 29796, (Human) 10975, (Bovine) 281570, (Bovine) 616871, (Human) 7381, (Bovine) 282393, (Human) 7384, (Bovine) 282394, (Human) 7385, (Bovine) 287020, (Human) 7386, (Bovine) 613899, (Human) 7388, (Bovine) 286885, (Human) 27089, (Rat) 685322, (Mouse) 66152, (Mouse) 66594, (Rat) 690848, (Rat) 362897, (Mouse) 67530, (Rat) 301011, (Mouse) 22273, (Mouse) 67003, (Rat) 293448, (Mouse) 66694, (Rat) 291103, (Rat) 366448, (Mouse) 66576, (Mouse) 22272, (Rat) 497902
heme binding
electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
metal ion binding
molecular_function
iron ion binding
electron carrier activity
protein binding
ubiquinol-cytochrome-c reductase activity
catalytic activity
metalloendopeptidase activity
zinc ion binding
ubiquitin protein ligase binding
protein complex binding
2 iron, 2 sulfur cluster binding
oxidoreductase activity
oxidoreductase activity, acting on diphenols and related substances as donors
iron-sulfur cluster binding
reductase
oxidoreductase
metabolite interconversion enzyme
metalloprotease
mitochondrial electron transport, ubiquinol to cytochrome c
response to glucagon
transport
oxidation-reduction process
aerobic respiration
mitochondrial respiratory chain complex III assembly
hydrogen ion transmembrane transport
generation of precursor metabolites and energy
electron transport chain
oxidative phosphorylation
response to activity
protein processing
response to alkaloid
response to hormone
response to drug
response to antibiotic
subthalamus development
pons development
cerebellar Purkinje cell layer development
hippocampus development
thalamus development
hypothalamus development
pyramidal neuron development
midbrain development
biological_process
protein heterooligomerization
proteolysis
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