Product References
Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts.
The Journal of experimental medicine
Kerdidani D,Aerakis E,Verrou KM,Angelidis I,Douka K,Maniou MA,Stamoulis P,Goudevenou K,Prados A,Tzaferis C,Ntafis V,Vamvakaris I,Kaniaris E,Vachlas K,Sepsas E,Koutsopoulos A,Potaris K,Tsoumakidou M
50-5381-82 was used in Immunohistochemistry to characterize in the lungs a subset of antigen-presenting fibroblasts with tumor-suppressive properties and propose that cancer immunotherapies might be strongly dependent on in situ MHCII antigen presentation.
Mon Feb 07 00:00:00 EST 2022
Dysregulation of interaction between LOXhigh fibroblast and smooth muscle cells contributes to the pathogenesis of aortic dissection.
Theranostics
Chen Y,Zhang T,Yao F,Gao X,Li D,Fu S,Mao L,Liu F,Zhang X,Xu Y,Deng J,Li W,Fan G,Xiao C,Chen Y,Wang L,Guo W,Zhou B
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunohistochemistry
Thu Mar 10 00:00:00 EST 2022
Vascularized lymph node transplantation successfully reverses lymphedema and maintains immunity in a rat lymphedema model.
Bioengineering & translational medicine
Sakarya AH,Huang CW,Yang CY,Hsiao HY,Chang FC,Huang JJ
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunohistochemistry
Thu Sep 01 00:00:00 EDT 2022
Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity.
Nature immunology
Prados A,Onder L,Cheng HW,Mörbe U,Lütge M,Gil-Cruz C,Perez-Shibayama C,Koliaraki V,Ludewig B,Kollias G
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Fibroblastic reticular cell response to dendritic cells requires coordinated activity of podoplanin, CD44 and CD9.
Journal of cell science
de Winde CM,Makris S,Millward LJ,Cantoral-Rebordinos JA,Benjamin AC,Martínez VG,Acton SE
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Flow Cytometry
Thu Jul 15 00:00:00 EDT 2021
Fibroblastic reticular cell response to dendritic cells requires coordinated activity of podoplanin, CD44 and CD9.
Journal of cell science
de Winde CM,Makris S,Millward LJ,Cantoral-Rebordinos JA,Benjamin AC,Martínez VG,Acton SE
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Flow Cytometry
Thu Jul 15 00:00:00 EDT 2021
CLEC-2-dependent platelet subendothelial accumulation by flow disturbance contributes to atherogenesis in mice.
Theranostics
Tang C,Wang L,Sheng Y,Zheng Z,Xie Z,Wu F,You T,Ren L,Xia L,Ruan C,Zhu L
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Flow Cytometry
Mon Feb 07 00:00:00 EST 2022
CLEC-2-dependent platelet subendothelial accumulation by flow disturbance contributes to atherogenesis in mice.
Theranostics
Tang C,Wang L,Sheng Y,Zheng Z,Xie Z,Wu F,You T,Ren L,Xia L,Ruan C,Zhu L
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Flow Cytometry
Mon Feb 07 00:00:00 EST 2022
CLEC-2-dependent platelet subendothelial accumulation by flow disturbance contributes to atherogenesis in mice.
Theranostics
Tang C,Wang L,Sheng Y,Zheng Z,Xie Z,Wu F,You T,Ren L,Xia L,Ruan C,Zhu L
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Flow Cytometry
Mon Feb 07 00:00:00 EST 2022
Podoplanin drives dedifferentiation and amoeboid invasion of melanoma.
iScience
de Winde CM,George SL,Crosas-Molist E,Hari-Gupta Y,Arp AB,Benjamin AC,Millward LJ,Makris S,Carver A,Imperatore V,Martínez VG,Sanz-Moreno V,Acton SE
50-5381-82 was used in Flow cytometry/Cell sorting to define podoplanin as a functional biomarker for dedifferentiated invasive melanoma and a promising migrastatic therapeutic target.
Fri Sep 24 00:00:00 EDT 2021
Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes.
PLoS biology
Fujimoto N,He Y,D'Addio M,Tacconi C,Detmar M,Dieterich LC
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth.
eLife
Thacker VV,Dhar N,Sharma K,Barrile R,Karalis K,McKinney JD
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunocytochemistry
Tue Nov 24 00:00:00 EST 2020
Single cell RNA sequencing identifies TGFβ as a key regenerative cue following LPS-induced lung injury.
JCI insight
Riemondy KA,Jansing NL,Jiang P,Redente EF,Gillen AE,Fu R,Miller AJ,Spence JR,Gerber AN,Hesselberth JR,Zemans RL
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunofluorescence
Tue Mar 26 00:00:00 EDT 2019
Transcriptional profiling of breast cancer-associated lymphatic vessels reveals VCAM-1 as regulator of lymphatic invasion and permeability.
International journal of cancer
Dieterich LC,Kapaklikaya K,Cetintas T,Proulx ST,Commerford CD,Ikenberg K,Bachmann SB,Scholl J,Detmar M
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Flow Cytometry
Fri Nov 15 00:00:00 EST 2019
IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells.
Cell reports
Dubey LK,Ludewig B,Luther SA,Harris NL
50-5381 was used in Flow cytometry/Cell sorting to determine the source of CXCL3 responsible for attracting CXCR5+ dendritic cells.
Tue May 21 00:00:00 EDT 2019
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor.
Nature
Zacharias WJ,Frank DB,Zepp JA,Morley MP,Alkhaleel FA,Kong J,Zhou S,Cantu E,Morrisey EE
50-5381 was used in Immunohistochemistry to identify the AEP lineage as an evolutionarily conserved alveolar progenitor that represents a new target for human lung regeneration strategies.
Thu Mar 08 00:00:00 EST 2018
Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti-PD-1 treatment.
Proceedings of the National Academy of Sciences of the United States of America
Peranzoni E,Lemoine J,Vimeux L,Feuillet V,Barrin S,Kantari-Mimoun C,Bercovici N,Guérin M,Biton J,Ouakrim H,Régnier F,Lupo A,Alifano M,Damotte D,Donnadieu E
50-5381 was used in Immunohistochemistry-immunofluorescence to show that exclusion of CD8 T cells from tumour islets is correlated with a poor clinical outcome and low lymphocyte motility in human lung squamous-cell carcinomas.
Tue Apr 24 00:00:00 EDT 2018
Podoplanin is an important stromal prognostic marker in perihilar cholangiocarcinoma.
Oncology letters
Obulkasim H,Shi X,Wang J,Li J,Dai B,Wu P,Wang S,Wang X,Ding Y
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program.
Nature communications
Frye M,Taddei A,Dierkes C,Martinez-Corral I,Fielden M,Ortsäter H,Kazenwadel J,Calado DP,Ostergaard P,Salminen M,He L,Harvey NL,Kiefer F,Mäkinen T
50-5381 was used in Flow cytometry/Cell sorting to study whether extracellular matrix stiffness impacts lymphatic vascular development.
Tue Apr 17 00:00:00 EDT 2018
Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
Immunology and cell biology
Gurung HR,Carr MM,Carr DJ
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Stem cell function and stress response are controlled by protein synthesis.
Nature
Blanco S,Bandiera R,Popis M,Hussain S,Lombard P,Aleksic J,Sajini A,Tanna H,Cortés-Garrido R,Gkatza N,Dietmann S,Frye M
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunofluorescence
Thu Jun 16 00:00:00 EDT 2016
Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers.
Journal of hepatology
Lua I,Li Y,Zagory JA,Wang KS,French SW,Sévigny J,Asahina K
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunohistochemistry
Sun May 01 00:00:00 EDT 2016
Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers.
Journal of hepatology
Lua I,Li Y,Zagory JA,Wang KS,French SW,Sévigny J,Asahina K
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunohistochemistry
Sun May 01 00:00:00 EDT 2016
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Pdgfrb-Cre targets lymphatic endothelial cells of both venous and non-venous origins.
Genesis (New York, N.Y. : 2000)
Ulvmar MH,Martinez-Corral I,Stanczuk L,Mäkinen T
50-5381 was used in Flow cytometry/Cell sorting to show that Pdgfrb-Cre does not target YS HemEC or YS-derived erythro-myeloid progenitors.
Wed Jun 01 00:00:00 EDT 2016
Nonvenous origin of dermal lymphatic vasculature.
Circulation research
Martinez-Corral I,Ulvmar MH,Stanczuk L,Tatin F,Kizhatil K,John SW,Alitalo K,Ortega S,Makinen T
50-5381 was used in Flow cytometry/Cell sorting to investigate the origin of murine lymphatic vasculature, showing a significant contribution from nonvenous cells.
Fri May 08 00:00:00 EDT 2015
Chronic lung injury by constitutive expression of activation-induced cytidine deaminase leads to focal mucous cell metaplasia and cancer.
PloS one
Kitamura J,Uemura M,Kurozumi M,Sonobe M,Manabe T,Hiai H,Date H,Kinoshita K
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunohistochemistry
Mon Mar 30 00:00:00 EDT 2015
Alveolar progenitor and stem cells in lung development, renewal and cancer.
Nature
Desai TJ,Brownfield DG,Krasnow MA
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunofluorescence
Thu Mar 13 00:00:00 EDT 2014
Dendritic cells control fibroblastic reticular network tension and lymph node expansion.
Nature
Acton SE,Farrugia AJ,Astarita JL,Mourão-Sá D,Jenkins RP,Nye E,Hooper S,van Blijswijk J,Rogers NC,Snelgrove KJ,Rosewell I,Moita LF,Stamp G,Turley SJ,Sahai E,Reis e Sousa C
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunohistochemistry
Thu Oct 23 00:00:00 EDT 2014
Dendritic cells control fibroblastic reticular network tension and lymph node expansion.
Nature
Acton SE,Farrugia AJ,Astarita JL,Mourão-Sá D,Jenkins RP,Nye E,Hooper S,van Blijswijk J,Rogers NC,Snelgrove KJ,Rosewell I,Moita LF,Stamp G,Turley SJ,Sahai E,Reis e Sousa C
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunohistochemistry
Thu Oct 23 00:00:00 EDT 2014
Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury.
Hepatology (Baltimore, Md.)
Lua I,James D,Wang J,Wang KS,Asahina K
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunofluorescence
Tue Jul 01 00:00:00 EDT 2014
C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo.
Clinical and experimental immunology
Ruseva MM,Takahashi M,Fujita T,Pickering MC
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunofluorescence
Tue Apr 01 00:00:00 EDT 2014
Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.
Hepatology (Baltimore, Md.)
Asahina K,Tsai SY,Li P,Ishii M,Maxson RE,Sucov HM,Tsukamoto H
Published figure using Podoplanin monoclonal antibody (Product # 50-5381-82) in Immunofluorescence
Sun Mar 01 00:00:00 EST 2009