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Proteintech
HuR Monoclonal Antibody (1A11H2)
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产品信息
66549-1-IG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
1A11H2
抗原
HuR Fusion Protein Ag2249 (1-326 aa encoded by BC003376)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSNGYEDHM AEDCRGDIGR TNLIVNYLPQ NMTQDELRSL FSSIGEVESA KLIRDKVAGH SLGYGFVNYV TAKDAERAIN TLNGLRLQSK TIKVSYARPS SEVIKDANLY ISGLPRTMTQ KDVEDMFSRF GRIINSRVLV DQTTGLSRGV AFIRFDKRSE AEEAITSFNG HKPPGSSEPI TVKFAANPNQ NKNVALLSQL YHSPARRFGG PVHHQAQRFR FSPMGVDHMS GLSGVNVPGN ASSGWCIFIY NLGQDADEGI LWQMFGPFGA VTNVKVIRDF NTNKCKGFGF VTMTNYEEAA MAIASLNGYR LGDKILQVSF KTNKSHK (1-326 aa encoded by BC003376)
靶标信息
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); ELAV like 1; Elav-like generic protein; ELAV-like protein 1; embryonic lethal, abnormal vision, drosophila, homolog-like 1; Hu antigen R; HU-antigen A; Hu-antigen R; Human antigen R; HuR; MelG
基因别名: 2410055N02Rik; ELAV1; ELAVL1; Elra; Hua; HUR; MelG; W91709
UniProt ID: (Human) Q15717, (Mouse) P70372, (Rat) B5DF91
Entrez Gene ID: (Human) 1994, (Mouse) 15568, (Rat) 363854
mRNA splicing, via spliceosome
multicellular organism development
regulation of mRNA stability
positive regulation of translation
mRNA stabilization
negative regulation of gene silencing by miRNA
3'-UTR-mediated mRNA stabilization
regulation of stem cell population maintenance
regulation of translation
