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Proteintech
Cytokeratin 16 Monoclonal Antibody (2H4D8)
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Product Details
66802-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2H4D8
Immunogen
Cytokeratin 16 Fusion Protein Ag11240 (121-473 aa encoded by BC039169)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MQNLNDRLA SYLDKVRALE EANADLEVKI RDWYQRQRPS EIKDYSPYFK TIEDLRNKII AATIENAQPI LQIDNARLAA DDFRTKYEHE LALRQTVEAD VNGLRRVLDE LTLARTDLEM QIEGLKEELA YLRKNHEEEM LALRGQTGGD VNVEMDAAPG VDLSRILNEM RDQYEQMAEK NRRDAETWFL SKTEELNKEV ASNSELVQSS RSEVTELRRV LQGLEIELQS QLSMKASLEN SLEETKGRYC MQLSQIQGLI GSVEEQLAQL RCEMEQQSQE YQILLDVKTR LEQEIATYRR LLEGEDAHLS SQQASGQSYS SREVFTSSSS SSSRQTRPIL KEQSSSSFSQ GQSS (121-473 aa encoded by B C039169)
Target Information
KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CK-16; cytokeratin 16; Cytokeratin-16; focal non-epidermolytic palmoplantar keratoderma; K16; keratin 16, type I; Keratin, type I cytoskeletal 16; Keratin-16
Gene Aliases: CK16; FNEPPK; K16; K1CP; KRT16; KRT16A; NEPPK; PC1
UniProt ID: (Human) P08779
Entrez Gene ID: (Human) 3868
morphogenesis of an epithelium
inflammatory response
cytoskeleton organization
aging
cell proliferation
epidermis development
keratinocyte differentiation
negative regulation of cell migration
keratinization
hair cycle
innate immune response
intermediate filament cytoskeleton organization
keratinocyte migration
establishment of skin barrier
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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