Antibodies Inc

GFAP-R416WT Monoclonal Antibody (N206B/9), FL650

Name: GFAP-R416WT Monoclonal Antibody (N206B\/9), FL650
Brand: Antibodies Inc
SKU: 75-279-FL650

查看其他5个GFAP (R416WT)抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

Immunogen image

Immunogen Image GFAP-R416WT Monoclonal Antibody (N206B/9), FL650

产品信息

75-279-FL650

应用

建议稀释比

已发表文章

免疫组化（冰冻） (IHC (F))

Assay-dependent

免疫细胞化学 (ICC/IF)

Assay-dependent

酶联免疫吸附实验 (ELISA)

Assay-dependent

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

N206B/9

抗原

Synthetic peptide amino acids 411-422 of human GFAP (accession number P14136).

查看免疫原

偶联物

FL650 FL650 FL650

激发/发射光谱

655/676 nm

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Dry ice (international)

产品详细信息

For maximum recovery of product, centrifuge the vial prior to removing the cap.

Sequence of this protein is as follows: KTVEMRDGEV IK

靶标信息

GFAP (R416W) refers to a specific mutation in the GFAP gene, where arginine (R) at position 416 is substituted with tryptophan (W). GFAP, or Glial Fibrillary Acidic Protein, is an intermediate filament protein expressed in astrocytes, providing structural support to these glial cells in the central nervous system. The R416W mutation is associated with Alexander disease, a rare neurodegenerative disorder characterized by the accumulation of GFAP aggregates, leading to astrocyte dysfunction and progressive neurological impairment.

仅用于科研。不用于诊断过程。未经明确授权不得转售。