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Proteintech
COPA Recombinant Rabbit Monoclonal Antibody (230361G2)
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Product Details
83089-1-RR
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
230361G2
Immunogen
COPA fusion protein Ag34207
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: QLPVDHILAG SFETAMRLLH DQVGVIQFGP YKQLFLQTYA RGRTTYQALP CLPSMYGYPN RNWKDAGLKN GVPAVGLKLN DLIQRLQLCY QLTTVGKFEE AVEKFRSILL SVPLLVVDNK QEIAEAQQLI TICREYIVGL SVETERKKLP KETLEQQKRI CEMAAYFTHS NLQPVHMILV LRTALNLFFK LKNFKTAATF ARRLLELGPK PEVAQQTRKI LSACEKNPTD AYQLNYDMHN PFDICAASYR PIYRGKPVEK CPLSGACYSP EFKGQICRVT TVTEIGKDVI GLRISPLQFR
Target Information
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha coat protein; Alpha-coat protein; Alpha-COP; coatomer protein complex subunit alpha; Coatomer subunit alpha; HEP-COP; HEPCOP; proxenin; xenin
Gene Aliases: AIAISD; AILJK; alpha-COP; AU040324; COPA; HEP-COP; xenin
UniProt ID: (Human) P53621, (Mouse) Q8CIE6
Entrez Gene ID: (Human) 1314, (Mouse) 12847
intracellular protein transport
ER to Golgi vesicle-mediated transport
retrograde vesicle-mediated transport, Golgi to ER
intra-Golgi vesicle-mediated transport
signal transduction
protein transport
vesicle-mediated transport
pancreatic juice secretion
protein localization to axon
protein localization to cell leading edge
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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