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This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%
This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: abLIM-1; actin-binding double zinc finger protein; Actin-binding LIM protein 1; Actin-binding LIM protein family member 1
基因别名: 2210411C18Rik; 2610209L21Rik; 4833406P10Rik; 9330196J19Rik; Ablim; Ablim1; AV079770; AW060987; AW215784; Kiaa0059; Limab1; mKIAA0059
UniProt ID: (Mouse) Q8K4G5
Entrez Gene ID: (Mouse) 226251