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Abnova
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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MASRTVIIDH GSGFLKAGTA GWNEPQMVFP NIVNYLPCKE NPGPSYARRR VSLGIDICHP DTFSYPIERG RILNWEGVQY LWSFVLENHR REQEVPPVII TETPLREPAD RKKMLEILFE LLHVPSVLLA DQLQMSLYAS GLLTGVVVDS GYGLTRVQPF HQGRPLPASG KTLEFAGQDL SAYLLKSLFK EDCDRRCLFQ LETVAVTQMN KCYVPQNLGE ALDFRERQQS ALDESNTYQL PDGSRVELTP MQRVAPEMFF SPQVFEQPGP SIPRAIVESV ESCEISLRPL LVSHVMACGG NTLYPGFTKR LFRELMGDHV SSTKATVWEG SNRNFSVWLG ASVVAHLSTY QSEWMSREEY GEHMRM
Actin-like protein 8 (ACTL8), also known as Cancer/Testis Antigen 57 (CT57), is part of the cancer/testis antigen (CTA) family. It is primarily expressed in the testes but aberrantly overexpressed in various cancers, including lung adenocarcinoma, endometrial cancer, and colorectal cancer. ACTL8's overexpression is associated with enhanced cell mobility, proliferation, and colony formation, contributing to tumor growth and poor prognosis. The gene is believed to play a critical role in oncogenesis and is being investigated as a potential therapeutic target due to its involvement in tumorigenic processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: actin like protein; actin-like 8; Actin-like protein 8; Cancer/testis antigen 57; CT57
基因别名: ACTL8; CT57
UniProt ID: (Human) Q9H568
Entrez Gene ID: (Human) 81569