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Recommended positive controls: 293T, mouse liver.
Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (97%), Dog (100%), Chicken (98%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: actin-related protein 1 alpha; actin-related protein 1 homolog A; Actin-RPV; Alpha-centractin; ARP1; ARP1 actin-related protein 1 homolog A, centractin alpha; Arp1 centractin alpha; Arp1 contractin alpha; Centractin; Centrosome-associated actin homolog; FLJ52695; FLJ52800; FLJ55002; yeast homolog A
基因别名: ACTR1A; alpha-Arp1; ARP1; Arp1A; CTRN1
UniProt ID: (Human) P61163, (Mouse) P61164
Entrez Gene ID: (Human) 10121, (Mouse) 54130