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Invitrogen
ACTR3B Polyclonal Antibody
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ACTR3B Antibody (PA5-96824) in WB
Western blot analysis of ACTR3B in extracts of various cell lines. Samples were incubated with ACTR3B Polyclonal antibody (Product # PA5-96824) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-96824
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 189-418 of human ACTR3B (NP_0651781)
偶联物
形式
Liquid
浓度
0.38 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: CIKHIPIAGR DITYFIQQLL REREVGIPPE QSLETAKAIK EKYCYICPDI VKEFAKYDVD PRKWIKQYTG INAINQKKFV IDVGYERFLG PEIFFHPEFA NPDFMESISD VVDEVIQNCP IDVRRPLYKN VVLSGGSTMF RDFGRRLQRD LKRVVDARLR LSEELSGGRI KPKPVEVQVV THHMQRYAVW FGGSMLASTP EFFQVCHTKK DYEEYGPSIC RHNPVFGVMS; Positive Samples: HeLa, NCI-H125, Mouse brain; Cellular Location: Cell projection, Cytoplasm, cytoskeleton
靶标信息
ACTR3B plays a role in the organization of the actin cytoskeleton.ACTR3B may function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. ACTR3B may decrease the metastatic potential of tumors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Actin-like protein 3B; actin-related protein 3-beta; Actin-related protein 3B; actin-related protein Arp11; Actin-related protein ARP4; ARP3 actin-related protein 3 homolog B; ARP3-beta; DKFZp686O24114
基因别名: 9630005C02; ACTR3B; ARP11; Arp3b; ARP3BETA; ARP4; AW047569
UniProt ID: (Human) Q9P1U1, (Mouse) Q641P0
Entrez Gene ID: (Human) 57180, (Mouse) 242894
