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Invitrogen
ADAMTS2 Polyclonal Antibody
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ADAMTS2 Antibody (PA5-87766) in WB
Western blot analysis of ADAMTS2 in extracts of various cell lines. Samples were incubated with ADAMTS2 Polyclonal antibody (Product # PA5-87766) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-87766
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
形式
Liquid
浓度
1.47 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: A-375, U-87MG, THP-1, Rat thymus, ; Cellular Location: extracellular matrix, extracellular space
Immunogen sequence: PRNISDPSKK SYVVQWLSRP DPDSPIRKIS SKGHCQGDKS IFCRMEVLSR YCSIPGYNKL CCKSCNLYNN LTNVEGRIEP PPGKHNDIDV FMPTLPVPTV AMEVRPSPST PLEVPLNASS TNATEDHPET NAVDEPYKIH GLEDEVQPPN LIPRRPSPYE KTRNQRIQEL IDEMRKKEML GKF
靶标信息
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in two transcript variants. The short transcript encodes a protein which has no significant procollagen N-peptidase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 2; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2; ADAM; ADAM-TS 2; ADAMs; metalloendopeptidases; PC I-NP; pNPI; Procollagen I N-proteinase; Procollagen I/II amino propeptide-processing enzyme; Procollagen N-endopeptidase
基因别名: ADAM-TS2; ADAMTS-2; ADAMTS-3; ADAMTS2; NPI; PC I-NP; PCI-NP; PCINP; PCPNI; PNPI; RGD1565950
UniProt ID: (Human) O95450
Entrez Gene ID: (Human) 9509, (Rat) 287899
