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Invitrogen
AJAP1 Polyclonal Antibody
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产品信息
PA5-78684
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the Intracellular domain of human AJAP1. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.9 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: rat liver
Predicted Reactivity: Human (100%), Mouse (91%), Bovine (93%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
AJAP1, Adherens Junction Associated Protein 1, plays a key role in cell adhesion and cell migration. It is a transmembrane protein found on the basolateral surface of epithelium and expressed by multiple types of epithelium. AJAP1 interacts with E-Cadherin and appears to promote the internalization of E-Cadherin upon growth factor stimulation. This facilitates the dissolution of adherens junctions with an increase in cell motility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adherens junction associated protein 1; Adherens junction-associated protein 1; Membrane protein shrew-1; Neumo48; RP3426F10.1; transmembrane protein SHREW1
基因别名: AJAP1; MOT8; Neumo48; SHREW-1; SHREW1
UniProt ID: (Human) Q9UKB5, (Rat) Q4W8E7
Entrez Gene ID: (Human) 55966, (Rat) 687031
