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Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alpha-1,2-glucosyltransferase ALG10-A; Alpha-2-glucosyltransferase ALG10-B; asparagine-linked glycosylation 10 homolog B (yeast, alpha-1,2-glucosyltransferase); asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B; Asparagine-linked glycosylation protein 10 homolog B; dolichyl-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-dolichol alpha-1,2- glucosyltransferase; modifier of the HERG potassium channel; potas; Potassium channel regulator 1; putative alpha-1,2-glucosyltransferase ALG10-B; Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase
基因别名: ALG10; ALG10B; KCR1
UniProt ID: (Human) Q5I7T1
Entrez Gene ID: (Human) 144245
分子生物学功能: transferase