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Immunogen sequence: AELRPNQGTL SLFTNEAGGI LDDLIVTNTS EGHLYVVSNA GCWEKDLALM QDKVRELQNQ GRDVGLEVLD NALLALQGPT AAQVLQAGVA DDLRKLPFMT SAVMEVFGVS GCRVTRCGYT GEDGVEISVP VAGAVHLATA ILKNPEVKLA GLAARDSLRL EAGLCLYGND IDEHTTPVEG SLSWTLGKRR RAAMDFPGAK VIVPQLKGRV QRRRVGLMCE GAPMRAHSPI LNMEGTKIGT VTSGCPSPSL KKNVAMGYVP CEYSRPGTML LVELPSGPCF
The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE) may be due to a defect in any one of these enzymes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: aminomethyltransferase (glycine cleavage system protein T); Aminomethyltransferase, mitochondrial; GCVT; Glycine cleavage system T protein
基因别名: AMT; EG434437; GCE; GCST; GCVT; NKH
UniProt ID: (Human) P48728, (Mouse) Q8CFA2
Entrez Gene ID: (Human) 275, (Mouse) 434437, (Rat) 306586
分子生物学功能: methyltransferase