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Invitrogen
APBB2 Polyclonal Antibody
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APBB2 Antibody (PA5-101421) in IHC (P)
Immunohistochemistry analysis of APBB2 in human kidney cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with APBB2 polyclonal antibody (Product # PA5-101421) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-101421
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human APBB2(Accession Q92870), corresponding to amino acid residues Q493-E543.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total APBB2.
靶标信息
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta precursor protein and amyloid beta precursor-like protein 2. This protein contains two phosphotyrosine binding domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: amyloid beta (A4) precursor protein-binding family B member 2 isoform APBB2_1; amyloid beta (A4) precursor protein-binding family B member 2 isoform APBB2_2; amyloid beta (A4) precursor protein-binding, family B, member 2; Fe65-like 1; FE65L; protein Fe65-like 1; similar to the C-terminus of rat transcriptional activator FE65, SwissProt Accession Number P46933; unnamed protein product; zinc finger-like protein
基因别名: 2310007D03Rik; FE65L; FE65L1; RGD1562438; Rirl1; TR2L; Zfra
UniProt ID: (Human) Q92870, (Mouse) Q9DBR4
Entrez Gene ID: (Human) 323, (Rat) 305338, (Mouse) 11787
negative regulation of transcription from RNA polymerase II promoter
neuron migration
regulation of transcription, DNA-templated
smooth muscle contraction
axon guidance
biological_process
extracellular matrix organization
maintenance of lens transparency
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
negative regulation of cell cycle phase transition
intracellular signal transduction
synapse organization
protein stabilization
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
