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Invitrogen
APC6 Polyclonal Antibody
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APC6 Antibody (PA5-121073) in IHC (P)
Immunohistochemistry analysis of APC6 in paraffin-embedded human gastric cancer. Samples were incubated with APC6 Polyclonal antibody (Product # PA5-121073) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-121073
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 371-620 of human CDC16 (NP_003894.3).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.89 mg/mL
规格
189 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: Jurkat, HepG2, HeLa, A-549, Mouse brain, Mouse ovary, Rat brain. The target is usually found in the following locations: Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, spindle.
Immunogen sequence: MLYIGLEYGL TNNSKLAERF FSQALSIAPE DPFVMHEVGV VAFQNGEWKT AEKWFLDALE KIKAIGNEVT VDKWEPLLNN LGHVCRKLKK YAEALDYHRQ ALVLIPQNAS TYSAIGYIHS LMGNFENAVD YFHTALGLRR DDTFSVTMLG HCIEMYIGDS EAYIGADIKD KLKCYDFDVH TMKTLKNIIS PPWDFREFEV EKQTAEETGL TPLETSRKTP DSRPSLEETF EIEMNESDMM LETSMSDHST
靶标信息
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Anaphase-promoting complex subunit 6; APC6; CDC16 cell division cycle 16 homolog; CDC16 homolog; CDC16Hs; cell division cycle 16 homolog; Cell division cycle protein 16 homolog; Cyclosome subunit 6; RP11-569D9.4
基因别名: 2700071J12Rik; 2810431D22Rik; ANAPC6; APC6; CDC16
UniProt ID: (Mouse) Q8R349
Entrez Gene ID: (Rat) 290875, (Mouse) 69957
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