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Invitrogen
ARIH2 Polyclonal Antibody
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ARIH2 Antibody (PA5-114879) in ICC/IF
Immunocytochemistry analysis of ARIH2 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114879) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with Alexa Fluor 594 conjugated goat anti-rabbit IgG (red) using a dilution of 1:600.
产品信息
PA5-114879
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ARIH2(Accession O95376), corresponding to amino acid residues N311-A361.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total ARIH2.
靶标信息
E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: all-trans retinoic acid inducible RING finger; ARI-2; ariadne 2; ariadne homolog 2; E3 ubiquitin-protein ligase ARIH2; FLJ10938; FLJ33921; OTTHUMP00000210388; protein ariadne-2 homolog; Triad1 protein; UbcM4-interacting protein 48
基因别名: AI843547; ARI2; ARIH2; HT005; TRIAD1; UIP48
UniProt ID: (Human) O95376, (Mouse) Q9Z1K6
Entrez Gene ID: (Human) 10425, (Mouse) 23807, (Rat) 316005
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin conjugating enzyme binding
ubiquitin protein ligase activity
nucleic acid binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
protein polyubiquitination
multicellular organism development
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
developmental cell growth
protein K63-linked ubiquitination
protein K48-linked ubiquitination
hematopoietic stem cell proliferation
positive regulation of protein targeting to mitochondrion
ubiquitin-dependent protein catabolic process
