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Invitrogen
ASC1 Polyclonal Antibody
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产品信息
PA5-53458
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ILQRDSNKSQ KLLKKLMSGV ENSGKVDIST KDLLPHQELR IKSGLEKAIK HKDKLLEFDR TSIRRTQVID DESDYFASDS NQWLSKLERE TLQKREEELR ELRHASRLSK KVTIDFAGRK ILEEENSLA
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.
靶标信息
Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; transcription coactivator Asc1; TRIP-4; zinc finger, C2HC5-type
基因别名: 4930558E03Rik; ASC-1; ASC1; BB191711; HsT17391; RQT4; SMABF1; TRIP4; ZC2HC5
UniProt ID: (Human) Q15650, (Mouse) Q9QXN3
Entrez Gene ID: (Human) 9325, (Rat) 315769, (Mouse) 56404
protease binding
transcription coactivator activity
protein binding
zinc ion binding
ligand-dependent nuclear receptor binding
estrogen receptor binding
histone acetyltransferase binding
ubiquitin-like protein ligase binding
metal ion binding
transcription cofactor
gene-specific transcriptional regulator
