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Invitrogen
AVPR1A Polyclonal Antibody
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AVPR1A Antibody (720364) in IHC
Sections of human pancreas were dewaxed, microwaved in citric acid and incubated with Anti-vasopressin receptor 1A/AVPR1A Rabbit Polyclonal Antibody (Product # 720364 at a concentration of 2 µg/mL). Sections were then sequentially treated with biotinylated anti-rabbit IgG and AB solution. Sections were then developed in AEC and lightly counterstained with hematoxylin. Inset, for adsorption controls the antibody was incubated with 10 µg/mL of the peptide used for immunizations (+ Peptide). Note, staining of pancreatic islets is completely n... View More
产品信息
720364
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to Human AVPR1A (aa 398-418)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 30% glycerol, 0.1% BSA
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
This antibody is predicted to react with Monkey, Rabbit and Cat.
靶标信息
Vasopressin receptor 1a (AVPR1A) is a receptor for arginine vasopressin. The activity of this receptor is mediated by G-proteins which activate a phosphatidyl-inositol-calcium second messenger system. AVPR1A has been involved in social behaviors, including affiliation and attachment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Antidiuretic hormone receptor 1a; AVPR V1a; SCCL vasopressin subtype 1a receptor; V1-vascular vasopressin receptor AVPR1A; V1a receptor; V1a vasopressin receptor; V1aR; Vascular/hepatic-type arginine vasopressin receptor; Vasopressin V1a receptor; Vasopressin V1aR
基因别名: AVPR V1a; AVPR1; AVPR1A; V1aR
UniProt ID: (Human) P37288
Entrez Gene ID: (Human) 552
regulation of systemic arterial blood pressure by vasopressin
maternal aggressive behavior
positive regulation of systemic arterial blood pressure
generation of precursor metabolites and energy
G-protein coupled receptor signaling pathway
activation of phospholipase C activity
positive regulation of cytosolic calcium ion concentration
negative regulation of female receptivity
grooming behavior
blood circulation
positive regulation of cell proliferation
positive regulation of heart rate
positive regulation of glutamate secretion
myotube differentiation
calcium-mediated signaling
telencephalon development
positive regulation of cell growth
positive regulation of prostaglandin biosynthetic process
positive regulation of cellular pH reduction
cellular response to hormone stimulus
social behavior
positive regulation of renal sodium excretion
cellular response to water deprivation
maternal behavior
sperm ejaculation
penile erection
positive regulation of vasoconstriction
response to corticosterone
negative regulation of transmission of nerve impulse
response to peptide
