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Invitrogen
African Swine Fever Virus Structural Protein p54 Polyclonal Antibody
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African Swine Fever Virus Structural Protein p54 Antibody (PA5-119520) in WB
Western blot analysis of African Swine Fever Virus Structural Protein p54 in Non-transfected (-) and transfected (+) 293T whole cell extracts (30 µg). Sample was separated with 15% SDS-PAGE, incubated with polyclonal African Swine Fever Virus Structural Protein p54 antibody (Product # PA5-119520) at a dilution of 1:5000, and followed by HRP-conjugated anti-rabbit IgG.
产品信息
PA5-119520
应用
建议稀释比
已发表文章
产品规格
种属反应
Virus
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of ASFV p54 (ASFV (strain: BA71V)). The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.55 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, we recommend adding 50% glycerol, then aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
靶标信息
The African Swine Fever Virus (ASFV) structural protein p54, encoded by the E183L gene, is a crucial component of the virus's architecture, playing a significant role in its morphogenesis. This 25-kDa polypeptide is essential for the recruitment of envelope precursors to assembly sites, contributing to the formation of viral particles. It is highly antigenic and has been localized within the replication factories of infected cells, predominantly associated with membranes and immature virus particles. The protein p54 has been shown to interact with target cells, aiding in the virus's attachment and entry, alongside other viral proteins like p30. Attempts to inactivate the p54 gene have demonstrated its necessity for ASFV replication, underscoring its potential as a target for therapeutic interventions. Its structural and functional properties make p54 a focal point of study in the development of ASFV treatments and prevention strategies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: African swine fever virus p54
