Invitrogen

Aquaporin 1 Polyclonal Antibody

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说明书
实验方案
问题与答案
技术支持
Aquaporin 1 Polyclonal Antibody

产品信息

PA5-120324

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:100-1:500
-

免疫组化（石蜡） (IHC (P))

1:50-1:200
-

免疫细胞化学 (ICC/IF)

1:50-1:200
-

酶联免疫吸附实验 (ELISA)

1 µg/mL
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to a sequence within amino acids 200-269 of human Aquaporin-1 (AQP1) (NP_9327661)
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.46 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.05% ProClin 300

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2913896

产品详细信息

Positive test controls include: Mouse liver, Mouse heart, Rat lung. The target is usually found in the following locations: Cell membrane, Multi-pass membrane protein.

Immunogen sequence: AVITHNFSNH WIFWVGPFIG GALAVLIYDF ILAPRSSDLT DRVKVWTSGQ VEEYDLDADD INSRVEMKPK

靶标信息

Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: AQP 1; AQP CHIP; AQP-1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; Channel-like integral membrane protein of 28 kDa; channel-like integral membrane protein, 28-kDa; CHIP 28; Colton blood group; Delayed early response protein 2; DER2; growth factor-induced delayed early response protein; MGC26324; Urine water channel; water channel protein for red blood cells and kidney proximal tubule

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基因别名: AQP-CHIP; AQP1; CHIP28; CO

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UniProt ID: (Human) P29972, (Mouse) Q02013, (Rat) P29975

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Entrez Gene ID: (Human) 358, (Mouse) 11826, (Rat) 25240

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功能
intracellular cGMP activated cation channel activity potassium channel activity water transmembrane transporter activity protein binding ammonium transmembrane transporter activity potassium ion transmembrane transporter activity glycerol transmembrane transporter activity water channel activity glycerol channel activity transmembrane transporter activity nitric oxide transmembrane transporter activity carbon dioxide transmembrane transporter activity transporter activity ephrin receptor binding transporter
参与通路
renal water homeostasis renal water transport cGMP biosynthetic process potassium ion transport water transport cell volume homeostasis cellular water homeostasis carbon dioxide transport ammonium transport bicarbonate transport glycerol transport cellular homeostasis lateral ventricle development pancreatic juice secretion nitric oxide transport establishment or maintenance of actin cytoskeleton polarity cerebrospinal fluid secretion cellular response to stress cellular response to UV transepithelial water transport carbon dioxide transmembrane transport odontogenesis response to drug negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of angiogenesis positive regulation of saliva secretion positive regulation of fibroblast proliferation multicellular organismal water homeostasis cellular response to hydrogen peroxide cellular response to inorganic substance cellular response to mechanical stimulus cellular response to copper ion cellular response to mercury ion cellular response to retinoic acid cellular response to cAMP cellular response to hypoxia cellular response to salt stress cellular hyperosmotic response cellular response to dexamethasone stimulus cellular response to nitric oxide potassium ion transmembrane transport ammonium transmembrane transport maintenance of symbiont-containing vacuole by host glomerular filtration transport positive regulation of lamellipodium assembly positive regulation of epithelial cell migration organic cation transport sensory perception of pain water homeostasis positive regulation of cell migration secretion by cell secretory granule organization carbohydrate transmembrane transport wound healing lipid digestion camera-type eye morphogenesis corticotropin secretion transmembrane transport renal water absorption cation transmembrane transport hyperosmotic response response to hormone hyperosmotic salinity response response to estrogen metanephric descending thin limb development metanephric proximal straight tubule development metanephric proximal convoluted tubule segment 2 development metanephric glomerulus vasculature development
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