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Invitrogen
BDKRB2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-50488
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues near the C terminal of human bradykinin receptor B2
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.1 mg/mL
规格
110 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total BDKRB2 protein.
靶标信息
Bradykinin B2 receptor (BDKRB2) expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, and kidney libraries. It is associated with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: B-2 bradykinin receptor gene; B2 bradykinin receptor; B2-bradykinin receptor gene; B2R; BK-2 receptor; BK-2R; BK-2Rs; DKFZp686O088; G-protein coupled receptor; kinin B2; unnamed protein product
基因别名: B(2); B2; B2R; BDKRB2; BK-2; BK2; BK2R; BKR2; BRB2
UniProt ID: (Human) P30411, (Mouse) P32299
Entrez Gene ID: (Human) 624, (Mouse) 12062
protease binding
phosphatidylinositol phospholipase C activity
G-protein coupled receptor activity
bradykinin receptor activity
protein binding
type 1 angiotensin receptor binding
protein heterodimerization activity
signal transducer activity
beta-2 adrenergic receptor binding
G-protein coupled receptor
system process
smooth muscle contraction
inflammatory response
signal transduction
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
response to salt stress
regulation of vasoconstriction
vasoconstriction
vasodilation
regulation of vascular permeability
arachidonic acid secretion
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
acute inflammatory response to antigenic stimulus
response to stress
negative regulation of cell proliferation
negative regulation of peptidyl-serine phosphorylation
maintenance of blood-brain barrier
negative regulation of blood pressure
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