Invitrogen

BIKE Polyclonal Antibody

Name: BIKE Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-114911
Availability: InStock

查看其他7个BIKE抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

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BIKE Antibody (PA5-114911) in WB

Western blot analysis of BIKE in various samples (Lane 1: Rat lung, treated with blocking peptide Lane 2: Rat lung; Lane 3: Mouse lung). Samples were incubated with polyclonal antibody (Product # PA5-114911).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image BIKE Polyclonal Antibody

产品信息

PA5-114911

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human BMP2K(Accession Q9NSY1), corresponding to amino acid residues S599-R649.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Affinity chromatography

保存液

PBS with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2899547

产品详细信息

Antibody detects endogenous levels of total BMP2K.

靶标信息

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. BMP2K (BMP2 inducible kinase), also known as BIKE, is a 1,161 amino acid nuclear protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Thought to be involved in osteoblast differentiation, BMP2K catalyzes the ATP-dependent phosphorylation of bone morphogenic proteins (BMPs); proteins that are essential for proper cartilage and bone formation. Via its catalytic activity, BMP2K may play a role in signaling pathways that mediate bone growth and cellular differentiation. Three isoforms of BMP2K exist due to alternative splicing events.

仅用于科研。不用于诊断过程。未经明确授权不得转售。