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Antibody detects endogenous levels of total C13orf18.
This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: KIAA0226-like; Pacer; Protein associated with UVRAG as autophagy enhancer; Protein Rubicon-like; similar to chromosome 13 open reading frame 18
基因别名: C13orf18; KIAA0226L; RUBCNL
UniProt ID: (Human) Q9H714
Entrez Gene ID: (Human) 80183, (Rat) 290403
分子生物学功能: protein-binding activity modulator phosphatase inhibitor phosphatase modulator