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Invitrogen
CATSPER4 Polyclonal Antibody
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产品信息
PA5-60965
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GQQQRITFSE TGAEEEEEND QLPLVHCVVA RSEKSGLLQE PLAGGPLSNL SENTCDNFCL VLEAIQENLR QYKEIRD
Highest antigen sequence identity to the following orthologs: Mouse - 62%, Rat - 71%.
靶标信息
CatSper4, is a protein which in humans is encoded by the CATSPER4 gene. CatSper1 is a member of thecation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells. Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cation channel sperm-associated protein 4; cation channel, sperm associated 4; CatSper4; CTSR4; ion channel CatSper4
基因别名: CATSPER4
UniProt ID: (Human) Q7RTX7
Entrez Gene ID: (Human) 378807
multicellular organism development
neuronal action potential
sperm motility
response to progesterone
regulation of ion transmembrane transport
sperm-egg recognition
sodium ion transmembrane transport
sperm capacitation
regulation of postsynaptic membrane potential
calcium ion transmembrane transport
membrane depolarization during action potential
