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Invitrogen
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Immunogen sequence: RSSGSSGCPS PTPQSSDPDD TPPKLLPETV SPSAPSWREP EVLDLSLPPE SAATSKRAPP EVTAAAG
Antigen sequence identity: Mouse 75%; Rat 78%
Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex. Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes. Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRromatin Organization MOdifier) domain. This domain plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: chromobox homolog 6; Chromobox protein homolog 6
基因别名: CBX6
UniProt ID: (Human) O95503
Entrez Gene ID: (Human) 23466