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Invitrogen
CCAR1 Polyclonal Antibody
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CCAR1 Antibody (PA5-78532) in ICC/IF
CCAR1 Polyclonal Antibody detects CCAR1 protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: A431 cells were fixed in ice-cold MeOH for 5 min. Green: CCAR1 protein stained by CCAR1 Polyclonal Antibody (Product # PA5-78532) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-78532
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
C. elegans,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human CCAR1. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: 293T, A431, HeLa, HepG2
Predicted Reactivity: Rat (97%), Xenopus laevis (82%), Xenopus Tropicalis (84%), Rhesus Monkey (100%), Bovine (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
IFI-44 (interferon-induced protein 44), also known as p44 or MTAP44 (microtubule-associated protein 44), is a 444 amino acid protein that localizes to the cytoplasm and, upon induction by IFN-betas, aggregates to form microtubular structures. Human IFI-44 shares 97% sequence similarity with its chimp counterpart, suggesting a conserved role between species. The gene encoding IFI-44 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CARP-1; Cell cycle and apoptosis regulatory protein 1; Cell division cycle and apoptosis regulator protein 1; Death inducer with SAP domain; MGC44628; OTTHUMP00000019709; RP11-437A18.1
基因别名: 2610511G16Rik; 9430036H15Rik; CARP1; CCAR1; DIS
UniProt ID: (Human) Q8IX12, (Mouse) Q8CH18
Entrez Gene ID: (Human) 55749, (Mouse) 67500
mRNA splicing, via spliceosome
transcription, DNA-templated
regulation of transcription, DNA-templated
apoptotic process
cell cycle
positive regulation of cell proliferation
positive regulation of cell migration
negative regulation of nucleic acid-templated transcription
positive regulation of apoptotic process
regulation of nucleic acid-templated transcription
