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Invitrogen
CCDC53 Polyclonal Antibody
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产品信息
PA5-58349
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PLNVTSVTNG AHPEATSEQP QQNSTQDSGL QESEVSAENI LTVAKDPRYA RYLKMVQVGV PVMAIRNKMI SEGLDPDLLE RPDAPVPDGE SEKTVEESSD SES
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.
靶标信息
Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Coiled-coil domain-containing protein 53; WASH complex subunit 3
基因别名: AD-016; CCDC53; CGI-116; WASHC3; x0009
UniProt ID: (Human) Q9Y3C0
Entrez Gene ID: (Human) 51019
