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Invitrogen
CCK Polyclonal Antibody
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产品信息
PA5-32348
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
C. elegans,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within Human Cholecystokinin aa 50 to the C-terminus (N terminal).
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.6, with 1% BSA
内含物
0.1% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is stomach tissue.
靶标信息
Cholecystokinin (CCK) is a neuropeptide hormone and neurotransmitter widely distributed throughout the gastrointestinal (GI) tract and the central nervous system (CNS). Antibodies that react specifically with CCK are useful for the study of the mode of action, differential tissue expression and intracellular and subcellular localization of CCK in the CNS and periphery as well as in neuroendocrine cells of the digestive system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CCK; Cholecystokinin; cholecystokinin octapeptide; cholecystokinin triacontatriapeptide; prepro-cholecystokinin
基因别名: CCK
UniProt ID: (Human) P06307
Entrez Gene ID: (Human) 885
behavioral fear response
neuron migration
release of cytochrome c from mitochondria
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
protein kinase C-activating G-protein coupled receptor signaling pathway
axonogenesis
positive regulation of cell proliferation
positive regulation of glutamate secretion
negative regulation of appetite
positive regulation of protein oligomerization
eating behavior
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of mitochondrial depolarization
regulation of sensory perception of pain
