Invitrogen

CD14 Monoclonal Antibody (TuK4), PE

Name: CD14 Monoclonal Antibody (TuK4), PE
Brand: Invitrogen
SKU: MA1-82234

1 篇参考文献

查看其他173个CD14抗体

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

产品信息

MA1-82234

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

Neat-1:10

其他PubMed (Misc)

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产品规格

种属反应

Bovine, Dog, Camelid, Cynomolgus monkey, Cat, Goat, Human, Mink, Sheep, Pig, Rabbit

已发表种属

Human

宿主/亚型

Mouse / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

TuK4

抗原

Proprietary Immunogen.

偶联物

PE PE PE

激发/发射光谱

565/576 nm 查看光谱

形式

Lyophilized

浓度

Conc. Not Determined

纯化类型

Protein A

保存液

PBS with 1% BSA, 5% sucrose

内含物

0.09% sodium azide

保存条件

4°C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

AB_927595

产品详细信息

Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4°C in the dark.

For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

Mouse anti human CD14 antibody, clone TÜK4 recognizes the human CD14 cell surface antigen.

靶标信息

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

生物信息学

蛋白别名: CD 14; CD14; CD14 antigen; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell-specific leucine-rich glycoprotein; sCD14; soluble CD14

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基因别名: CD14

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UniProt ID: (Rabbit) Q28680, (Human) P08571, (Bovine) Q95122