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Invitrogen
CD2BP2 Polyclonal Antibody
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CD2BP2 Antibody (PA5-103190) in ICC/IF
Immunofluorescent analysis of CD2BP2 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with CD2BP2 polyclonal antibody (Product # PA5-103190) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
产品信息
PA5-103190
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CD2BP2(Accession O95400), corresponding to amino acid residues D104-A154.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CD2 Tail-binding.
靶标信息
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD2 (cytoplasmic tail) binding protein 2; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2; protein phosphatase 1, regulatory subunit 59; U5 snRNP 52K protein; U5-52K
基因别名: 1500011B02Rik; 2410024K20Rik; AW048183; CD2BP2; FWP010; KIAA1178; LIN1; PPP1R59; Snu40; U5-52K
UniProt ID: (Human) O95400, (Mouse) Q9CWK3
Entrez Gene ID: (Human) 10421, (Mouse) 70233
