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Invitrogen
CD4/HLA-DR Antibody Cocktail, FITC, PE
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Product Details
MA1-12281
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Cocktail
Type
Antibody
Clone
7E14, 423L
Immunogen
human peripheral blood T lymphocytes
Conjugate
FITC , PE
FITC , PE
FITC , PE
Form
Liquid
Purification
Protein A/G
Storage buffer
PBS with 0.2% carrier protein
Contains
0.08% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is a monoclonal mixture of FITC-conjugated CD4 (clone 7E14, isotype IgG1) and PE-conjugated HLADR (clone 423L, isotype IgG2a).
Target Information
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD4 antigen (p55); CD4 antigen p55; CD4 receptor; CD74 antigen; T-cell surface antigen T4/Leu-3; T4 surface glycoprotein precursor; unnamed protein product
Gene Aliases: CD4mut; IMD79; Leu-3; OKT4D; T4
UniProt ID: (Human) P01730
Entrez Gene ID: (Human) 920
virus receptor activity
transmembrane signaling receptor activity
receptor binding
extracellular matrix structural constituent
protein binding
zinc ion binding
lipid binding
coreceptor activity
immunoglobulin binding
enzyme binding
protein kinase binding
MHC class II protein complex binding
signaling receptor activity
interleukin-16 binding
interleukin-16 receptor activity
MHC class II protein binding
identical protein binding
protein homodimerization activity
protein tyrosine kinase binding
positive regulation of immune system process
immune response
cell adhesion
signal transduction
cell surface receptor signaling pathway
enzyme linked receptor protein signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of calcium ion transport into cytosol
T cell differentiation
macrophage differentiation
leukocyte chemotaxis
response to estradiol
maintenance of protein location in cell
positive regulation of interleukin-2 production
response to vitamin D
helper T cell enhancement of adaptive immune response
interleukin-15-mediated signaling pathway
positive regulation of T cell proliferation
T cell activation
T cell selection
response to ethanol
positive regulation of monocyte differentiation
viral entry into host cell
positive regulation of inflammatory response
T cell receptor signaling pathway
regulation of T cell activation
positive regulation of multicellular organismal process
cellular response to granulocyte macrophage colony-stimulating factor stimulus
response to methamphetamine hydrochloride
cellular response to ionomycin
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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