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FIGURE: 1 / 2
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total SLC3A2.
CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4F2 cell-surface antigen heavy chain; 4F2 heavy chain antigen; 4F2hc; Amino acid transporter heavy chain SLC3A2; antigen identified by monoclonal antibodies 4F2; CD98; Lymphocyte activation antigen 4F2 large subunit; slc3a2 {ECO:0000312|RGD:3073}; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; Solute carrier family 3 member 2; solute carrier family 3, member 2
Gene Aliases: MDU1; SLC3A2
UniProt ID: (Rat) Q794F9
Entrez Gene ID: (Rat) 50567
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