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Invitrogen
CDCA7L Polyclonal Antibody
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CDCA7L Antibody (PA5-23443) in WB
Western blot analysis of CDCA7L in HCT-116 cell lysate in the 1) absence and 2) presence of immunizing peptide and 3) NIH 3T3 cell lysate using this antibody at 4 µg/mL and 2 µg/mL, respectively. Samples were incubated in CDCA7L polyclonal antibody (Product # PA5-23443) followed by a goat anti-rabbit Ig HRP secondary antibody. PicoTect ECL substrate solution was used for this test.
产品信息
PA5-23443
产品规格
种属反应
Human,
Mouse,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A portion of amino acid 170 to 220 of human CDCA7L/RAM2.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen displays the following percentage of sequence identity for non-tested species: Mouse/Rat/Equine (89%), Bovine (84%).
靶标信息
Cell division cycle-associated 7-like protein (or RAM2) is a transcription factor which plays a role in transcriptional regulation and apoptotic signaling pathways. It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to promoter. It also plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell division cycle associated 7-like; Cell division cycle-associated 7-like protein; Protein JPO2; Transcription factor RAM2
基因别名: BC006933; CDCA7L; HR1; JPO2; R1; RAM2
UniProt ID: (Human) Q96GN5, (Mouse) Q922M5
Entrez Gene ID: (Human) 55536, (Mouse) 217946
