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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Predicted to react with Mouse samples.
CDH12 is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BR-cadherin; Brain cadherin; Cadherin; Cadherin-12; N-cadherin 2; Neural type cadherin 2
基因别名: CDH12; Cdhb
UniProt ID: (Mouse) Q5RJH3
Entrez Gene ID: (Mouse) 215654