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Invitrogen
CDX2 Polyclonal Antibody
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产品信息
PA5-95733
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 14-165 of human CDX2 (NP_0012563)
偶联物
形式
Liquid
浓度
0.53 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: SW620, MCF7; Cellular Location: Nucleus
Immunogen sequence: YPSSVRHSGG LNLAPQNFVS PPQYPDYGGY HVAAAAAAAA NLDSAQSPGP SWPAAYGAPL REDWNGYAPG GAAAAANAVA HGLNGGSPAA AMGYSSPADY HPHHHPHHHP HHPAAAPSCA SGLLQTLNPG PPGPAATAAA EQLSPGGQRR NL
靶标信息
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: caudal type homeo box 2; caudal type homeo box transcription factor 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX-3; HGNC:1806; Homeobox protein CDX-2; homeobox protein miniCDX2
基因别名: Cdx-2; CDX-3; CDX2; CDX2/AS; CDX3
UniProt ID: (Human) Q99626, (Mouse) P43241
Entrez Gene ID: (Human) 1045, (Mouse) 12591, (Rat) 66019
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
DNA binding
double-stranded DNA binding
protein binding
sequence-specific DNA binding
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
blood vessel development
trophectodermal cell differentiation
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
endosome to lysosome transport
organ morphogenesis
anterior/posterior axis specification
regulation of somitogenesis
cell differentiation
somatic stem cell population maintenance
establishment or maintenance of epithelial cell apical/basal polarity
positive regulation of cell differentiation
positive regulation of transcription, DNA-templated
intestinal epithelial cell differentiation
labyrinthine layer development
blastocyst development
placenta development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
multicellular organism development
pattern specification process
anterior/posterior pattern specification
