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产品信息
PA5-30815
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 201 of Human CHMP6
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548289
产品详细信息
Recommended positive controls: 293T, A431, Jurkat, Raji.
Predicted reactivity: Mouse (95%), Rat (96%), Chicken (81%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 ).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Charged multivesicular body protein 6; chromatin modifying protein 6; Chromatin-modifying protein 6; hVps20; Vacuolar protein sorting-associated protein 20; Vps20
基因别名: CHMP6; VPS20
UniProt ID: (Human) Q96FZ7
Entrez Gene ID: (Human) 79643
