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Invitrogen
CK2 beta Polyclonal Antibody
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产品信息
PA5-29703
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human Casein Kinase 2 beta. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (99%), Xenopus laevis (100%), Pig (100%), Rabbit (100%), Chicken (100%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alternative name: G5a, phosvitin; casein kinase 2, beta polypeptide; Casein kinase II beta subunit; Casein kinase II subunit beta; CK II beta; CSNK2B; CSNK2B-LY6G5B-1072; CSNK2B-LY6G5B-1103; CSNK2B-LY6G5B-532; CSNK2B-LY6G5B-560; CSNK2B-LY6G5B-562; DADB-127H9.2; MGC138222; MGC138224; Phosvitin; Protein G5a; protein kinase; unnamed protein product
基因别名: CK2B; CK2N; Ckb1; Ckb2; CSK2B; CSNK2B; G5A; POBINDS
UniProt ID: (Human) P67870
Entrez Gene ID: (Human) 1460
chromatin binding
protein serine/threonine kinase activity
receptor binding
protein binding
protein kinase regulator activity
protein domain specific binding
protein binding, bridging
identical protein binding
metal ion binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
signal transduction
negative regulation of cell proliferation
Wnt signaling pathway
peptidyl-threonine phosphorylation
release from viral latency
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of activin receptor signaling pathway
adiponectin-activated signaling pathway
negative regulation of blood vessel endothelial cell migration
positive regulation of SMAD protein import into nucleus
endothelial tube morphogenesis
protein-containing complex assembly
symbiont-mediated disruption of host cell PML body
negative regulation of viral life cycle
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