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Proteintech
SERCA3 Monoclonal Antibody (1A2C2), CoraLite® Plus 488
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产品信息
CL488-68287
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1A2C2
抗原
SERCA3 fusion protein Ag4527
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1000 µg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Sequence of this protein is as follows: TRRMARKNAI VRSLPSVETL GCTSVICSDK TGTLTTNQMS VCRMFVVAEA DAGSCLLHEF TISGTTYTPE GEVRQGDQPV RCGQFDGLVE LATICALCND SALDYNEAKG VYEKVGEATE TALTCLVEKM NVFDTDLQAL SRVERAGACN TVIKQLMRKE FTLEFSRDRK SMSVYCTPTR PHPTGQGSKM FVKGAPESVI ERCSSVRVGS RTAPLTPTSR EQILAKIRDW GSGSDTLRCL ALATRDAPPR KEDMELDDCS KFVQYETDLT FVGCVGMLDP PRPEVAACIT RCYQAGIRVV MITGDNKGTA VAICRRLGIF GDTEDVAGKA YTGREFDDLS PEQQRQACRT ARCFARVEPA HKSRIVENLQ SFNEITAMTG DGVNDAPALK KAEIGIAMGS GTAVAKSAAE MVLSDDNFAS IVAAVEEGRA IYSNMKQFIR YLISSNVGEV VCIFLTAILG LPEALIPVQL LWVNLVTDGL PATALGFNPP DLDIMEKLPR SPREALISGW LFFRYLAIGV YVGLATVAAA TWWFVYDAEG PHINFYQLRN FLKCSEDNPL FAGIDCEVFE SRFPTTMALS VLVTIEMCNA LNSVSENQSL LRMPPWMNPW LLVAVAMSMA LHFLILLVPP LPLIFQVTPL SGRQWVVVLQ ISLPVILLDE ALKYLSRNHM HEEMSQK
靶标信息
ATP dependent calcium pumps are responsible in part for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium ATPases (SERCA). The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific isoform expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. SERCA3 has been found to co-express with SERCA2b in platelets, mast cells, lymphoid cells, and epithelial cells. Due to this pattern of expression it is referred to as the non-muscle form of SERCA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adenosine triphosphatase, calcium; ATPase, Ca(2+)-transporting, ubiquitous; ATPase, Ca++ transporting, ubiquitous; Calcium pump 3; calcium-translocating P-type ATPase; sarco/endoplasmic reticulum Ca2+ -ATPase; sarcoendoplasmic reticulum Ca2+ ATPase type 3; Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA3; SR Ca(2+)-ATPase 3
基因别名: ATP2A3; SERCA3; SERCA3b
UniProt ID: (Human) Q93084, (Rat) P18596, (Mouse) Q64518
Entrez Gene ID: (Human) 489, (Rat) 25391, (Mouse) 53313
