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Proteintech
MYBPC3 Monoclonal Antibody (3C8F8), CoraLite® 594
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Product Details
CL594-67608
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3C8F8
Immunogen
MYBPC3 fusion protein Ag15848
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MPEPGKKPV SAFSKKPRSV EVAAGSPAVF EAETERAGVK VRWQRGGSDI SASNKYGLAT EGTRHTLTVR EVGPADQGSY AVIAGSSKVK FDLKVIEAEK AEPMLAPAPA PAEATGAPGE APAPAAELGE SAPSPKGSSS AALNGPTPGA PDDPIGLFVM RPQDGEVTVG GSITFSARVA GASLLKPPVV KWFKGKWVDL SSKVGQHLQL HDSYDRASKV YLFELHITDA QPAFTGSYRC EVSTKDKFDC SNFNLTVHEA MGTGDLDLLS AFRRTSLAGG GRRISDSHED TGILDFSSLL KKRDSFRTPR DSKLEAPAEE DVWEILRQA
Target Information
Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments. It modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Mutations affecting the gene can result in cardiomyopathy - familial hypertrophic 4, cardiomyopathy - dilated 1MM, or left ventricular non-compaction 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-protein, cardiac muscle isoform; cardiac C-protein; Cardiac MyBP-C; DKFZp779E1762; myosin binding protein C, cardiac; Myosin-binding protein C, cardiac-type; truncated cardiac myosin-binding protein C
Gene Aliases: CMD1MM; CMH4; FHC; LVNC10; MYBP-C; MYBPC3
UniProt ID: (Human) Q14896, (Rat) P56741
Entrez Gene ID: (Pig) 100628050, (Human) 4607, (Rat) 295929, (Mouse) 17868
regulation of heart rate
heart morphogenesis
muscle contraction
regulation of striated muscle contraction
cell adhesion
regulation of heart contraction
myosin filament assembly
sarcomere organization
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
muscle filament sliding
positive regulation of ATPase activity
regulation of muscle filament sliding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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