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Invitrogen
CLIC4 Polyclonal Antibody
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CLIC4 Antibody (PA5-28146) in ICC/IF
Immunocytochemistry (Confocal immunofluorescence) of CLIC4 in paraformaldehyde-fixed HeLa. Samples were incubated with CLIC4 polyclonal antibody (Product # PA5-28146) using a dilution of 1:500 (green). Alpha-tubulin filaments were labeled with alpha Tubulin monoclonal antibody (Product # MA1-25054) (Red) at 1:2,500.
产品信息
PA5-28146
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human CLIC4. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.83 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HeLa, Raji.
Predicted reactivity: Mouse (98%), Rat (96%), Zebrafish (85%), Xenopus laevis (87%), Rhesus Monkey (99%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: chloride intracellular channel 4 like; Chloride intracellular channel protein 4; DKFZP566G223; FLJ38640; Glutaredoxin-like oxidoreductase CLIC4; Intracellular chloride ion channel protein p64H1
基因别名: CLIC4; CLIC4L; H1; huH1; MTCLIC; p64H1
UniProt ID: (Human) Q9Y696
Entrez Gene ID: (Human) 25932
angiogenesis
endothelial cell morphogenesis
glutathione metabolic process
chloride transport
apoptotic process
vacuolar acidification
fertilization
cell differentiation
keratinocyte differentiation
negative regulation of cell migration
regulation of ion transmembrane transport
establishment or maintenance of apical/basal cell polarity
multicellular organism growth
branching morphogenesis of an epithelial tube
regulation of cytoskeleton organization
retina vasculature morphogenesis in camera-type eye
cellular response to calcium ion
chloride transmembrane transport
