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Invitrogen
CNDP2 Polyclonal Antibody
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产品信息
PA5-30694
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human CNDP2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.59 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: 293T, A431, Jurkat, Raji, mouse brain.
Predicted reactivity: Mouse (92%), Rat (92%), Zebrafish (81%), Xenopus laevis (80%), Pig (89%), Chicken (85%), Rhesus Monkey (93%), Chimpanzee (98%), Bovine (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The CNDP2 gene encodes the protein carnosine dipeptidase 2, which belongs to the M20 metallopeptidase family and plays a critical role in the metabolism of dipeptides. CNDP2 is primarily involved in the hydrolysis of carnosine, a dipeptide composed of beta-alanine and histidine, and is expressed in various tissues, including the liver and kidney. This enzyme is significant in cellular processes related to nitrogen metabolism and the regulation of histidine-containing dipeptides, which have antioxidant properties influencing cellular redox balance. CNDP2 has implications in renal function and disease, where altered activity can impact the concentration of bioactive peptides involved in protective mechanisms against oxidative stress. Additionally, CNDP2 may have roles in metabolic diseases, such as diabetes and hypertension, where dipeptide regulation can influence metabolic pathways and cellular protection mechanisms. Ongoing research explores CNDP2's enzymatic activity, regulation, and potential therapeutic applications, particularly in conditions where modulation of peptide metabolism can offer clinical benefits.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: carnosine dipeptidase II; CNDP dipeptidase 2; Cytosolic non-specific dipeptidase; cytosolic nonspecific dipeptidase; epididymis secretory protein Li 13; Glutamate carboxypeptidase-like protein 1; peptidase 1; Peptidase A; Threonyl dipeptidase
基因别名: 0610010E05Rik; C76600; CN2; CNDP2; CPGL; Dip-2; HEL-S-13; HsT2298; Pep-1; Pep1; PEPA
UniProt ID: (Human) Q96KP4, (Mouse) Q9D1A2
Entrez Gene ID: (Human) 55748, (Mouse) 66054
