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Invitrogen
CNPY3 Polyclonal Antibody
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CNPY3 Antibody (PA5-96600) in IHC (P)
Immunohistochemistry analysis of CNPY3 in paraffin-embedded mouse kidney. Samples were incubated with CNPY3 Polyclonal antibody (Product # PA5-96600) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-96600
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 31-278 of human CNPY3 (NP_0065772)
偶联物
形式
Liquid
浓度
0.49 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GPSQAGAEEN DWVRLPSKCE VCKYVAVELK SAFEETGKTK EVIGTGYGIL DQKASGVKYT KSDLRLIEVT ETICKRLLDY SLHKERTGSN RFAKGMSETF ETLHNLVHKG VKVVMDIPYE LWNETSAEVA DLKKQCDVLV EEFEEVIEDW YRNHQEEDLT EFLCANHVLK GKDTSCLAEQ WSGKKGDTAA LGGKKSKKKS SRAKAAGGRS SSSKQRKELG GLEGDPSPEE DEGIQKASPL THSPPDEL; Positive Samples: HepG2, MCF7, THP-1, HL-60, U-937; Cellular Location: Endoplasmic reticulum
靶标信息
PRAT4A is a novel protein belonging to the canopy family with a saposin B-type domain. It is an accessory molecule required for microbial recognition by Toll-like receptor (TLR), and mediates TLR dependent immune responses. Though the exact function of PRAT4A is still unknown, reports suggest that it is associated with the immature form of TLR4 and regulates the cell surface expression of this TLR. PRAT4A, a secreted protein, also has a role in TLR4 maturation and glycosylation. PRATA4 is usually present in endoplasmic reticulum and plays an active role in regulating the subcellular distribution and response of multiple TLRs and is required for both innate and adaptive immune responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAG repeat containing; CAG/CTG 5; CTG repeat protein 4a; Expanded repeat-domain protein CAG/CTG 5; Protein associated with TLR4; protein associated with Toll-like receptor 4A; Protein canopy homolog 3; Trinucleotide repeat-containing gene 5 protein
基因别名: 1600025D17Rik; 2410050O22Rik; AI413153; CAG4A; CNPY3; CTG4A; ERDA5; HSPC084; PRAT4A; TNRC5; UNQ1934/PRO4409
UniProt ID: (Human) Q9BT09, (Mouse) Q9DAU1
Entrez Gene ID: (Human) 10695, (Mouse) 72029
