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Probable catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Amplification-dependent oncogene; promotes cell proliferation and tumorigenesis by down- regulating expression of the tumor suppressor protein, PML. May play a role in the pathogenesis of the lung cancer development and progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: casein kinase 2, alpha 1 polypeptide pseudogene; casein kinase 2, alpha 3 polypeptide; Casein kinase II alpha 1 polypeptide pseudogene; Casein kinase II subunit alpha 3; CK II alpha 3
基因别名: CSNK2A1P; CSNK2A3
UniProt ID: (Human) Q8NEV1
Entrez Gene ID: (Human) 283106